Homing Endonuclease Browser

Wild-Type Homing Endonucleases

Name

-11

-10

-9

-8

-7

-6

-5

-4

-3

-2

-1

1

2

3

4

5

6

7

8

9

10

11

I-AabMI

A

G

G

T

A

C

C

C

T

T

T

A

A

A

C

C

T

A

C

T

A

A

I-AniI

C

T

G

A

G

G

A

G

G

T

T

T

C

T

C

T

G

T

A

A

A

G

I-CeuI

A

T

A

A

C

G

G

T

C

C

T

A

A

G

G

T

A

G

C

G

A

A

I-CkaMI

A

A

G

T

A

C

C

C

T

T

T

A

A

A

C

C

T

A

A

T

T

A

I-CpaMI

T

A

G

C

C

C

A

C

A

A

T

A

T

T

A

A

G

G

C

C

A

T

I-CraMI

A

G

T

A

G

T

G

A

A

G

T

A

T

G

T

T

G

T

T

T

A

A

I-CreI

G

A

A

A

A

C

G

T

C

G

T

G

A

G

A

C

A

G

T

T

T

C

I-DmoI

C

G

C

C

G

G

A

A

C

T

T

A

C

C

C

G

G

C

A

A

G

G

I-GpeMI

T

T

T

C

C

G

C

T

T

A

T

T

C

A

A

C

C

C

T

T

T

A

I-GpiI

T

T

T

T

C

C

T

G

T

A

T

A

T

G

A

C

T

T

A

A

A

T

I-GzeI

G

C

C

C

C

T

C

A

T

A

A

C

C

C

G

T

A

T

C

A

A

G

I-GzeII

A

T

G

G

G

T

A

C

C

A

T

A

T

T

G

G

T

A

C

A

A

A

I-HjeMI

T

T

G

A

G

G

A

G

G

T

T

T

C

T

C

T

G

T

T

A

A

T

I-LtrI

A

A

T

G

C

T

C

C

T

A

T

A

C

G

A

C

G

T

T

T

A

G

I-LtrWI

A

G

T

A

G

T

G

A

A

G

T

A

T

G

T

T

A

T

T

T

A

A

I-MpeMI

T

A

G

A

T

A

A

C

C

A

T

A

A

G

T

G

G

C

T

A

A

T

I-MsoI

C

A

G

A

A

C

G

T

C

G

T

G

A

G

A

C

A

G

T

T

C

C

I-OnuI

T

T

T

C

C

A

C

T

T

A

T

T

C

A

A

C

C

T

T

T

T

A

I-PanMI

G

C

T

C

C

T

C

A

T

A

A

T

C

C

T

T

A

T

C

A

A

G

I-SceI

A

C

G

C

T

A

G

G

G

A

T

A

A

C

A

G

G

G

T

A

A

T

I-SmaMI

T

A

T

C

C

T

C

C

A

T

T

A

T

C

A

G

G

T

G

T

A

C

I-SscMI

A

G

G

T

A

C

C

C

T

T

T

A

A

A

C

C

T

A

T

T

A

A

I-Vdi141I

C

T

G

A

C

T

C

T

C

T

T

A

A

G

G

T

A

G

C

C

A

A

PI-SceI

C

T

A

T

G

T

C

G

G

G

T

G

C

G

G

A

G

A

A

A

G

A

Engineered Homing Endonucleases

Name

-11

-10

-9

-8

-7

-6

-5

-4

-3

-2

-1

1

2

3

4

5

6

7

8

9

10

11

I-CreI (m)

G

A

A

A

A

C

G

T

C

G

T

G

A

G

A

C

A

G

T

T

T

C

I-MsoI (m)

C

A

G

A

A

C

G

T

C

G

T

G

A

G

A

C

A

G

T

T

C

C

I-OnuI (E2)

G

G

T

C

C

A

C

A

T

A

T

T

T

A

A

C

C

T

T

T

T

G

Chimeric Homing Endonucleases

Name

-11

-10

-9

-8

-7

-6

-5

-4

-3

-2

-1

1

2

3

4

5

6

7

8

9

10

11

I-AniI / I-OnuI

C

T

G

A

G

G

A

G

G

T

T

T

C

A

A

C

C

T

T

T

T

A

I-DmoI / I-CreI

C

G

C

C

G

G

A

A

C

T

T

G

A

G

A

C

A

G

T

T

T

C

I-GpiI / I-OnuI

T

T

T

T

C

C

T

G

T

A

T

T

C

A

A

C

C

T

T

T

T

A

I-GzeI / I-PanMI

G

C

C

C

C

T

C

A

T

A

A

T

C

C

T

T

A

T

C

A

A

G

I-LtrI / I-PanMI

A

A

T

G

C

T

C

C

T

A

T

T

C

C

T

T

A

T

C

A

A

G

I-OnuI / I-LtrI

T

T

T

C

C

A

C

T

T

A

T

A

C

G

A

C

G

T

T

T

A

G

Putative and/or Pseudo-Endonucleases

Name

I-AaeMIP

I-ApaMIP

I-GzeMIIIP

I-NcrMIP

I-OsoMIIP

I-OsoMIP

I-PanMIIIP

I-PanMIIP

I-ScuMIIIP

I-ScuMIIP

I-ScuMIP

I-ScuMIVP